The offense had 71 plays in week 2 - up from 58 in week 1. With Donald Stephenson leaving after 8 plays with an injury to his calf, our string of games where all five offensive lineman played 100% of the offensive snaps ended at one game.
| Player | Game 1 | Game 2 |
| Stephenson | 100% | 11% |
| Okung | 100% | 100% |
| Schofield | 100% | 100% |
| Paradis | 100% | 100% |
| Garcia | 100% | 100% |
| Siemian | 100% | 100% |
| Sanders | 86% | 85% |
| Anderson | 83% | 66% |
| Thomas | 76% | 79% |
| Green | 71% | 58% |
| Norwood | 52% | 56% |
| Janovich | 47% | 48% |
| Latimer | 29% | 25% |
| Taylor | 22% | 14% |
| Phillips | 10% | 35% |
| Weems | 10% | 89% |
| Booker | 10% | 20% |
| Bibbs | 3% | 14% |
The biggest gainer on offense was Darrion Weems, because of the injury to Stephenson. Weems went from 6 snaps as the 6th offensive lineman to 63 snaps. Devontae Booker (6 to 14) and Kapri Bibbs (2 to 10) both looked to be gaining snaps in an effort to keep CJ Anderson fresh.
The defense was on the field for 73 plays against the Colts. Darien Stewart was an ironman taking all 73 of our defensive snaps which is a rarity in a Wade Phillips defense as he likes to keep players relatively fresh by rotating guys.
| Game 1 | Game 2 | |
| Harris | 95% | 92% |
| Ward | 89% | 90% |
| Stewart | 88% | 100% |
| Marshall | 84% | 89% |
| Talib | 82% | 81% |
| Miller | 77% | 70% |
| Crick | 75% | 73% |
| Williams | 66% | 55% |
| Wolfe | 66% | 77% |
| Davis | 63% | 55% |
| Roby | 63% | 64% |
| Ray | 52% | 62% |
| Ware | 44% | 18% |
| Simmons | 40% | 55% |
| Barrett | 30% | 37% |
| Winn | 30% | 21% |
| Nelson | 21% | 5% |
| Webster | 15% | 12% |
| Kilgo | 15% | 10% |
| Gotsis | 7% | 15% |
| Watson | 0% | 16% |
| Parks | 0% | 7% |
The biggest gainer on defense was Dekoda Watson and this was also due to injury. Watson had no defensive snaps in game 1 and he took 12 defensive snaps.