The biggest games to watch early on will be one AFC matchup and one NFC matchup, if you are interested in watching teams fight for their playoff lives. This fan certainly craves those kinds of games.
In the AFC, you have the Miami Dolphins on the road against the Buffalo Bills. The Dolphins must win out to have a shot at 6-7, but the Bills at 7-6 likely also need to win out. Add in the fact they are AFC East division rivals and this game should be a fun one.
In the NFC, Aaron Rodgers makes his return with the Green Bay Packers who at 7-6 are in desperation mode. The NFC is strong this year and 10-6 might not even be good enough, but with the Carolina Panthers (9-4) hosting the Packers the road to 10-6 might be impossible at this point.